TU Munich — TUM School of Engineering and Design — Professorship for Systems Biotechnology
The field of systems biotechnology deals with the application of systems biology methods and procedures to biotechnological problems. In recent years, systems biology has established itself as an interdisciplinary field of research, combining mathematical/theoretical approaches with experimental methods.
In addition to the improvement of the overall biotechnological process, the main focus of the research work is an improved understanding of the processes taking place in a cell. Pseudomonas putida, Escherichia coli and Halomonas elongata were selected as model organisms, all of which have high potential for biotechnological research.
The methodological focus of the department is the development of meaningful mathematical models, with the help of which the behavior of the cells is first described, but then also specifically influenced. This requires models with high predictive potential. To build and validate these models, experimental data from different cellular levels (metabolism, gene expression, and signal transduction) are merged with data from the process. For experimental work, the department has an S1 laboratory with attached work and evaluation room and a good equipment of analytical and measurement devices as well as cultivation facilities.