Mathematical models of cellular pathways are essential tools in systems biology and systems medicine. They contribute to an understanding of structure and dynamics of cellular processes far beyond their isolated parts, as well as the prevention, diagnosis and therapy of diseases. Yet, there are a variety of open questions. The International Conference on Integrative Pathway Modelling in Systems Biology and Systems Medicine will gather experts in pathway modelling to discuss the state-of-the-art in reuse, integration, visualization, and parameterization of models. Topics will be:
Modeling of signalling, metabolic and gene regulatory pathways
Modeling of diseases and therapies
Model and data standards
Model reuse, extension and integration
Parameter optimization
Identifiability and uncertainty analysis
Model analysis
Oral presentations will be delivered by invited speakers and selected from submitted abstracts. This includes short presentations on open problems and scientific questions. In addition, there will be poster presentations for in depth discussions. The discussion of open problems and possible solutions will be a core element, following the spirit of the COMBINE Meetings and the Workshop on ODE Modelling in Systems Biology. The 3‑day conference is complemented by a 2‑day hackathon. The hackathon will provide participants with time and space to work on tool-based integration of models. Complimentary, help with the implementation of community standards will be provided. The hackathon is intended to be a space to technically improve both models and tools. The aim is to work towards a combined model-data repository for integrative modeling. Conference and workshop are funded by the German Ministry for Education and Research (BMBF) via the e:Med Project INCOME. INCOME aims to facilitate scientific exchange and training to establish a platform for integrative model development.
Confirmed keynote speakers
Edda Klipp, Humboldt-Universität zu Berlin
Julio Saez-Rodriguez, RWTH Aachen University
Clemens Kreutz, University of Freiburg
Dirk Fey, University College Dublin
Benjamin M. Gyori, Harvard Medical School
Marc R. Birtwistle, Clemson University
Important Dates
Conference: October 15 — 17, 2018
Hackathon: October 18 — 19, 2018
Registration for conference, hackathon, or both.
Online registration closes: Monday, September 3, 2018
