International companies operating in the field of industrial biotechnology

Allylix Inc.
, a manufacturer of specialty chemicals from renewable resources combines biotechnological processes with molecular biological methods to develop and manufacture high-quality specialty chemicals. The company is headquartered in San Diego, USA.

Since March 2012, the Dutch research and technology company Avantium cooperates with Danone GmbH to produce a new generation of bio-based plastic bottles. These PEF bottles (Polyethylenfuranoat) shall be superior to the conventional PET bottles (polyethylene terephthalate) in their functional properties as well as the CO2 balance.

produces succinic acid from renewable raw materials in its facility in the French Pomacle. The system runs with an annual capacity of 3,000 tons. For 2013, BioAmber intends to launch a new large plant with an additional annual capacity of 17,000 tons at Lanxess’ site in Sarnia, Canada. (See also national users, Lanxess)

Braskem is a Brazilian company that has developed a process by which it can produce bio-polyethylene. A plant for the production of 200,000 tons of bio-polyethylene per year has come into operation in 2010. Another plant for the production of bio-polypropylene is planned for 2013.

Cargill NatureWorks LLC
is a leading manufacturer of biopolymers made from PLA (=polylactic acid). Already in 2003, a lactic acid-processing factory in Nebraska, USA, opened with a capacity of 140,000 tons per year.

One of the planned projects of the global company Dow Chemicals is a 350,000 ton plant in Brazil for the production of bio-polyethylene, in order to produce biopolymers.

Dupont and BP research on the production of bio-butanol from lignocellulose. Together with Tate & Lyle Dupont produces bio-1,3-propanediol for bio-based PTT (polytrimethylene terephthalate), which may be used in various fields as a biopolymer.

The aviation and aerospace group EADS N.V. agreed in March 2012 to cooperate together with Airbus, Boeing Co. and Embraer-Empresa Brasileira de Aeronáutica S.A. in the development of affordable "drop-in" biofuels for aviation. The goal is the reduction of CO2 emissions and fuel consumption despite increasing traffic.

Genencor makes fermentative isoprene for rubber and supplies e.g. Goodyear.

Genomatica and Novamont have signed a joint venture in August 2011to build a biorefinery. There, Genomatica's Bio-butanediol shall be produced and used in Novamont's bioplastic products.

The IBB network member Global Bioenergies S.A. develops artificial metabolic pathways to produce light olefins directly via fermentation, which can escape as gas from the culture medium. The company got in 2012 the award as "Most Innovative European Biotech SME" for their research and development in this area.

Lonza Group Ltd. is a global life science supplier and decided in April 2012 to develop with the Australian research agency CSIRO new products from recombinant produced bee silk proteins.

The French biotechnology company METabolic Explorer S.A. produces bulk chemicals from renewable resources. It develops industrial processes based on fermentation to offer an alternative to the limited fossil resources.

Pfizer produces ethyl(S)-4-chloro-3-hydroxybutyrate, a precursor of atorvastatin, using biotechnological methods. This cholesterol-lowering drug with the trade name Lipitor/Sortis had a turnover of 11.8 billion U.S. dollars in 2010, making it Pfizer's top-selling drug.

The Dutch company Purac has already completed in 2012 a lactide facility with 75,000 tons per year in Thailand. Lactide is used to produce the bioplastic PLA. Thus, Purac intends to take a leading role in the market for lactic acid-based bioplastics.

Roquette and DSM founded in 2010 a joint venture for the production of bio-based succinic acid. As a platform chemical, the succinic acid shall be further processed to butanediol, polyurethane resins and biopolymers, such as polybutylene succinate.

TRW Automotive Inc.
is a global automotive supplier. Since mid-2012, the company produces in series driver airbag modules with individual components of bio-based plastics.

The Finnish pulp and paper company UPM GmbH, with headquarters in Helsinki, is building in Lappeenranta a plant to produce from 2014 on annually 100,000 tons of second-generation biofuel. The German branch of UPM is based in Augsburg and is a member of IBB network.

The American VW subsidiary cooperates with the biofuel company Amyris and Solazyme to test the performance of their diesel technology using biofuels. Solazyme uses microalgae to produce oil for biofuels.

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