LMU München - Institut für Organische Chemie I
Management/LeitungProf. Dr. Herbert Mayr
BrancheForschung und Lehre
There are three research subjects at the institute for organic chemistry:
DNA hybrid materials: Synthesis of artificial functional nucleosides with special redox properties or metal-coordinating sites for the construction of new nanoscopic materials and machines.
DNA damage and repair: Synthesis of DNA lesions and lesion analogues, incorporation into DNA strands and investigation of the structure (x-ray, enzymatic digestion) and biological fate (repair experiments, mutagenicity) of the damaged oligonucleotides.
tRNA modifications: Total synthesis of natural modified RNA nucleosides, incorporation into RNA strands and investigation of the structure (x-ray, enzymatic digestion) as well as biological function.
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